17b hydroxysteroid dehydrogenase

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  1. Type 10 17b-hydroxysteroid dehydrogenase deficiency: Introduction
  2. Symptoms
  3. Causes
  4. Treatments
  5. Misdiagnosis
  6. Complications

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Principal supervisor : Exotoxicology (UniSA) (4) ; Carcinogenesis (UniSA) (2) ; Cancer prevention (UniSA) (2) ; Pharmacy (UniSA) (1) ; Oncology (Flinders) (1) ; Pharmacology (UniSA) (3) ; Medicinal Chemistry (UniSA) (1) ;
Associate supervisor : Ecotoxicology (UniSA) (2) ; Cancer prevention (UniSA) (1) ; Autism (UniSA) (1) ; Biochemistry (UniSA) (1) ; Drug Discovery (UniSA) (2) ; Pharmacology (Flinders) (1) ; Genetics (UniSA) (1) ;

17-β-Hydroxysteroid dehydrogenase III deficiency is clinically characterized by either ambiguous external genitalia or complete female external genitalia at birth; as a consequence of impaired male sexual differentiation in 46,XY individuals. Further investigations on ambiguous genitalia will eventually lead to findings of intersexuality . Severely impaired virilization (often complete absence of male sexual differentiation) can lead to development of female external genitalia. These children are raised as female, and their diagnosis is often discovered when there is absence of menarche (first menstruation) and when they begin to virilize during puberty (slowly become more like a man; deepening of the voice, acne, male musculature etc.). At careful examination, testis can often be found in the inguinal channel.

17b hydroxysteroid dehydrogenase

17b hydroxysteroid dehydrogenase

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