1. Twycross R, Wilcock A, Charlesworth S et al . Palliative Care Formulary (second edition). Radcliffe Medical Press, Oxford, 2003.
2. Watson M, Lucas C, Hoy A et al . Oxford Handbook of Palliative Care . Oxford University Press, Oxford, 2005.
3. Jehle PM. Steroid-induced osteoporosis: how can it be avoided? Nephrol Dial Transplant 2003; 18: 861-4.
4. Van Staa TP, Leyfkens HGM, Abenhaim L et al . Use of oral corticosteroids and risk of fractures. J Bone Miner Res 2000; 15: 993-1000.
5. Homik J, Cranney A, Shea B et al . Bisphosphonates for steroid induced osteoporosis. Cochrane Database Syst Rev 1999, Issue 1. Art No: CD001347. DOI: /.
6. Sambrook PN. How to prevent steroid induced osteoporosis. Ann Rheum Dis 2005; 64: 176-8.
7. Royal College of Physicians of London. Glucocorticoid-induced osteoporosis . RCP, London, 2002.
8. Bijlsma JWJ. Prevention of glucocorticoid induced osteoporosis. Ann Rheum Dis 1997; 56: 507-9.
9. Lips P. Prevention of corticosteroid induced osteoporosis. BMJ 1999; 318: 1366-7.
10. Homik J, Suarez-Almazor ME, Shea B et al . Calcium and vitamin D for corticosteroid-induced osteoporosis. Cochrane Database Syst Rev 1998, Issue 2. Art No: CD000952. DOI: /.
11. Sambrook PN, Kotowicz M, Nash P et al . Prevention and treatment of glucocorticoid induced osteoporosis: a comparison of calcitriol, vitamin D plus calcium and alendronate plus calcium. J Bone Miner Res 2003; 18: 919-24.
12. American College of Rheumatology Task Force on Osteoporosis Guidelines. Recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis (Update). Arthritis Rheum 2001; 44: 1496-1503.
13. National Osteoporosis Guideline Group. Guideline for the diagnosis and management of osteoporosis in postmenopausal women and men from the age of 50 years in the UK. NOGG , Sheffield, 2008.
14. Institute for Clinical Systems Improvement. Diagnosis and treatment of osteoporosis . Institute for Clinical Systems Improvement, Bloomington (MN), 2006.
Sex hormone-binding globulin (SHBG) is thought to mainly function as a transporter and reservoir for the estradiol and testosterone sex hormones. However it has also been demonstrated that SHBG can bind to a cell surface receptor (SHBG-R). The SHBG-R has not been completely characterized. A subset of steroids are able to bind to the SHBG/SHBG-R complex resulting in an activation of adenylyl cyclase and synthesis of the cAMP second messenger.  Hence the SHBG/SHBG-R complex appears to act as a transmembrane steroid receptor that is capable of transmitting signals to the interior of cells.
If you are going to start your first cycle soon, 'how to inject' is probably that last thing that you are worried about. You would have started by conducting research on the different injectable anabolic steroids available in the market, whichyou think can help you reach your goal. But when you have the vials and the syringes in front of you, you will surely think about how you will get the steroid out from the bottle and into your body. At this point, some people will become exasperated and even give up. Here is some information on injecting anabolic steroids.