Diagnostically, injections can be used to help determine which structure in the back is generating pain. If lidocaine or similar numbing medication is used, and the patient feels temporary relief after an anatomic region is injected (. facet joint or sacroiliac joint ), it can then be inferred that the specific region is the source of the pain. When considered in conjunction with a patient's history, physical exam, and imaging studies, injections used for diagnostic purposes can be very helpful in guiding further treatment for the patient.
There have been attempts to link squalene to Gulf War Syndrome mainly due to the idea that squalene might have been present in an anthrax vaccine given to some military personnel during the 1991 Persian Gulf War. Studies found that deployed Persian Gulf War Syndrome patients are significantly more likely to have antibodies to squalene (95 percent) than asymptomatic Gulf War veterans (0 percent; p<.001).   The first of these published results concludes with the following statement: "It is important to note that our laboratory-based investigations do not establish that squalene was added as adjuvant to any vaccine used in military or other personnel who served in the Persian Gulf War era." The second publication, however, links the incidence of anti-squalene antibodies and Gulf War Syndrome to five specific lots of vaccine. Furthermore, they cite results of 1999 testing by the . Food and Drug Administration which found these specific lots of vaccine to contain squalene.  In response to these results, a committee of the US Institute of Medicine stated that "The committee does not regard this study as providing evidence that the investigators have successfully measured antibodies to squalene", since the authors did not perform the normal scientific controls needed to show that their test was specific to anti-squalene antibodies.  It has also been determined that the anthrax vaccines given to those US military personnel did not use squalene as an adjuvant.    The vaccines were also tested for squalene, and none was detected with standard methods.  Another method found no squalene in 37 of the 38 lots tested. One lot contained traces of squalene, at less than ten parts per billion, which is about one-thirtieth the level found in human blood.  The FDA stated that this trace of squalene probably came from a fingerprint, since the oils on human skin contain enough squalene to send these extremely sensitive tests "off the chart". 
What is cortisone?
It is a hormone produced by a small gland on top of the kidney called the adrenal gland. It is essential to the proper functioning of your body, particularly when under stress. Its absence is known as Addison's Disease, which without treatment is fatal. Cortisone is a normal body product therefore; there are no allergic reactions. In cases of people with severe allergies, it is one of our most effective treatment tools. Cortisone by itself is rarely used today as it is relatively short acting and of low potency. Semi-artificial cortisone derivatives, such as DepoMedrol, Celestone, Kenalog, and a number of others, are used with increased benefits and fewer side effects.